CLINICAL THYROIDOLOGY
NOVEMBER 2008
VOLUME 20 ISSUE 3
Editor: Ernest L. Mazzaferri, MD
TABLE OF CONTENTS
Clinical Thyroidology November 2008 Entire Issue (PDF File, 1.75 MB, 35 pages)
(Note: the links below open the individual articles in this issue for saving and printing)
EDITOR’S COMMENTS
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 1.75 MB, 35 pages)
IN MEMORIAM Dr. Robert David Utiger
Clinical Thyroidology Volume 20 Issue 3 November 2008
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CONCISE REVIEW TSH Reference Limits: Emerging concepts and implications for the prevalence of subclinical hypothyroidism
Clinical Thyroidology Volume 20 Issue 3 November 2008
PDF (70.6 KB, pages 4-5)
EDITORIAL Levothyroxine therapy alone restores normal serum FT3 levels after total thyroidectomy
Clinical Thyroidology Volume 20 Issue 3 November 2008
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EDITOR’S CHOICE HYPOTHYROIDISM Levothyroxine therapy alone restores normal serum FT3 levels after total thyroidectomy
Jonklaas J, Davidson B, Bhagat S, Soldin SJ. Triiodothyronine levels in athyreotic individuals during levothyroxine therapy. JAMA 2008;299:769-77.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 231 KB, pages 8-9)
HYPOTHYROIDISM The diagnosis of subclinical hypothyroidism is severely limited by a single set of thyroid function tests and the biologic variation in thyroid testing from visit to visit
Karmisholt J, Andersen S, Laurberg P. Interval between tests and thyroxine estimation method influence outcome of monitoring of subclinical hypothyroidism. J Clin Endocrinol Metab 2008;93:1634-40.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 164 KB, pages 10-11)
NONTHYROIDAL EFFECTS OF RADIOIODINE Radioiodine therapy for women with thyroid cancer does not adversely affect subsequent pregnancies and those offspring over a 10-year follow-up period
Garsi JP, Schlumberger M, Rubino C, Ricard M, Labbe M, Ceccarelli C, Schvartz C, Henri-Amar M, Bardet S, De Vathaire F. Therapeutic administration of 131I for differentiated thyroid cancer: radiation dose to ovaries and outcome of pregnancies. J Nucl Med 2008;49:845-52.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 183 KB, pages 12-13)
THYROTOXICOSIS Patients with hyperthyroidism treated with radioiodine may be at increased risk of long-term morbidity and hospitalization for arrhythmias and cardiovascular disease
Metso S, Auvinen A, Salmi J, Huhtala H, Jaatinen P. Increased long-term cardiovascular morbidity among patients treated with radioactive iodine for hyperthyroidism. Clin Endocrinol (Oxf) 2008;68:450-7.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 136 KB, pages 14-15)
HYPERTHYROIDISM Patients with subclinical thyrotoxicosis experience significant improvements in mood and motor learning but have minor declines in self-perceived general and physical health status
Samuels MH, Schuff KG, Carlson NE, Carello P, Janowsky JS. Health status, mood, and cognition in experimentally induced subclinical thyrotoxicosis. J Clin Endocrinol Metab 2008;93:1730-6.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 169 KB, pages 15-16)
HYPERTHYROIDISM Subclinical thyrotoxicosis progresses to overt hyperthyroidism more often in Graves’ disease than with toxic nodular goiter
Rosario PW. The natural history of subclinical hyperthyroidism in patients below the age of 65 years. Clin Endocrinol (Oxf) 2008;68:491-2.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 165 KB, pages 18-19)
HYPERTHYROIDISM Widely metastatic follicular thyroid cancer may cause T3 thyrotoxicosis from increased tumor deiodinase activity identifiable only by serum T3 levels and stopping levothyroxine therapy
Miyauchi A, Takamura Y, Ito Y, Miya A, Kobayashi K, Matsuzuka F, Amino N, Toyoda N, Nomura E, Nishikawa M. 3,5,3´-Triiodothyronine thyrotoxicosis due to increased conversion of administered levothyroxine in patients with massive metastatic follicular thyroid carcinoma. J Clin Endocrinol Metab 2008;93:2239-42.
Clinical Thyroidology Volume 20 Issue 3 November 2008
PDF (149 KB, pages 20-21)
THYROID HORMONE THERAPY Levothyroxine absorption is not impaired in normal subjects treated short-term with gastric acid inhibitors famotidine or esomeprazole, or with ezetimibe
Ananthakrishnan S, Braverman LE, Levin RM, Magnani B, Pearce EN. The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption. Thyroid 2008;18:493-8.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 150 KB, pages 22-23)
THYROID HORMONE THERAPY Coffee interferes with the intestinal absorption of levothyroxine
Benvenga S, Bartolone L, Pappalardo MA, Russo A, Lapa D, Giorgianni G, Saraceno G, Trimarchi F. Altered intestinal absorption of L-thyroxine caused by coffee. Thyroid 2008; 18:293-301.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 179 KB, pages 24-25)
THYROID DISEASE Men with hyperthyroidism or hypothyroidism commonly have erectile dysfunction that often spontaneously improves after restoration to euthyroidism
Krassas GE, Tziomalos K, Papadopoulou F, Pontikides N, Perros P. Erectile dysfunction in patients with hyper- and hypothyroidism: how common and should we treat? J Clin Endocrinol Metab 2008;93:1815-9.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 165 KB, pages 26-27)
HYPERTHYROIDISM Patients with thyrotoxicosis, especially those with Graves’ disease, gain weight for up to 9 months after becoming euthyroid with antithyroid drug therapy
Rathi MS, Miles JN, Jennings PE. Weight gain during the treatment of thyrotoxicosis using conventional thyrostatic treatment. J Endocrinol Invest 2008;31:505-8.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 93.3 KB, pages 28-29)
THYROID CANCER The success rate of thyroid remnant ablation in low risk patients is greater using a fixed amount of 131I determined by tumor stage than selecting it according to a 24-hr 131I uptake
Verkooijen RB, Verburg FA, Van Isselt JW, Lips CJ, Smit JW, Stokkel MP. The success rate of I-131 ablation in differentiated thyroid cancer: comparison of uptake-related and fixed-dose strategies. Eur J Endocrinol 2008;159:301-7.
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 207 KB, pages 30-32)
THYROID CANCER PET/MRI fusion studies provide important information that may change decisions regarding surgical therapy for patients with thyroid cancer
Seiboth L, Van Nostrand D, Wartofsky L, Ousman Y, Jonklaas J, Butler C, Atkins F, Burman K. Utility of PET/neck MRI digital fusion images in the management of recurrent or persistent thyroid cancer. Thyroid 2008;18:103-11,
Clinical Thyroidology Volume 20 Issue 3 November 2008
(PDF File, 118 KB, pages 33-34)
CLINICAL THYROIDOLOGY, this highly valued abstract and commentary publication provides a broad-ranging look at the clinical thyroid literature. Experts in the field summarize the most cutting-edge, relevant articles that clinicians should know about and provide insight into the relevance and impact of each article on patient care.
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